THYROID FUNCTION TEST EVALUATION IN PROSTATE CANCER PATIENTS IN KHARTOUM STATE

Authors

  • Abdallah E. Ali University of Alzaeim Al Azhari Faculty of Medical Laboratory Sciences, Department of Clinical Chemistry
  • Sejood E. M. Abdalla University of Alzaeim Al Azhari Faculty of Medical Laboratory Sciences, Department of Clinical Chemistry
  • Ibrahim A. A. Karti Alofoug College of Science & Technology, Program of Medicine, Khartoum, Sudan
  • Haidar E. Saleh Miami University, Sylvester Comprehensive Cancer Center (SCCC) Clinical Research Laboratory Services Miami Fl33136 USA

Keywords:

Prostate cancer, Thyroid hormones, T3, T4, TSH, Prostate Antigen

Abstract

Thyroid hormones (TH) are key regulators of essential cellular processes, including proliferation,
differentiation, apoptosis, and metabolism. Thyroid hormones have an important role in the development of
prostate cancer. So this study aims to assess thyroid function tests among prostatic cancer patients.
Total group study100, fifty Prostatic cancer patients as a case study and 50 healthy men as the control group,
blood samples were collected for measurement for thyroid function test and Prostate Antigen by Tosoh TM
device (China) and enzyme-linked immune sorbent assay (ELISA) Fortress TM. Results: Statistical analysis of
test results of the case study: the mean and SD± PSA= (31.8 ± 12.5), T3 = (3.3 ± 1.3), T4 = (119.58 ± 46.21)
and TSH =(4.6 ± 3.4) . For each P-value 0.0001 when compared to the control group, the frequency of thyroid
disorders among case study participants is hyperthyroidism (33 = 66%), normal (14 = 28%), and
hypothyroidism (3 = 6%).Hyperthyroidism is the most common thyroid disorder among patients with prostatic
cancer.

Published

2022-02-11

How to Cite

Ali, A. E., Abdalla, S. E. M., Karti, I. A. A., & Haidar E, S. (2022). THYROID FUNCTION TEST EVALUATION IN PROSTATE CANCER PATIENTS IN KHARTOUM STATE. SADI International Journal of Science, Engineering and Technology (SIJSET), 9(1), 42–49. Retrieved from https://sadijournals.org/index.php/SIJSET/article/view/199

Issue

Vol. 9 No. 1 (2022): January-March, 2022

Section

Original Peer Review Articles
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